GLP-1 receptor agonists have proven to be the potent agents against type 2 diabetes in the contemporary battle, helping regulate blood sugar and promote weight loss. The two great treatments include Liraglutide and Semaglutide, among others. The two medications act in the same way as the natural hormone GLP-1 (glucagon-like peptide-1), a blood sugar-controlling hormone that slows gastric emptying and makes one feel full. But they have it in common that the functions are quite similar; however, the difference lies in the dosing, strength, and lifelong effect.
In this article, we will take a closer look at the role of Liraglutide in the administration of blood sugar and how the same is further improved through Semaglutide treatment.
What Is Liraglutide and What Does It Do to Control the Sugar Level of the Blood?
The Liraglutide prescription substance is labelled by trade names such as Victoza and Saxenda (weight loss), and it is daily treatment given via injection that is chiefly prescribed to:
- The reduced glucose levels on blood
- Protuberant weight loss
- Minimize happening of cardiovascular events among diabetics
It acts through the stimulation of the body of GLP-1 receptors which:
- Produce insulin secretion in cases where the blood sugar count is high
- Inhibit the secretion of glucagon (hormone that increases the blood sugar)
- Delay emptying of the stomach, which resulted in the decrease in hunger and better control of glucose levels after eating.
The Increased benefits of Semaglutide Therapy
Semaglutide is a second-generation GLP-1 receptor agonist marketed under Ozempic (type 2 diabetes), Wegoby (weight-loss), and Rybelsus (an oral drug against diabetes). It provides weekly administration, and better clinical outcomes than the previous drugs such as Liraglutide.
The main advantages of Semaglutide:
Better Control of Blood Sugar
As the clinical trials of Semaglutide against Liraglutide such as SUSTAIN illustrated, Semaglutide is more effective in reducing HbA1c than Liraglutide. This gives it an upper hand over persons who require a more precise glucose control.
More Weight Loss
Semaglutide has acquired a wide reputation as weight-loss medication. Indeed, Wegovy (semaglutide on obesity) has managed to make patients reduce their body weight in clinical trials by 1015% and this is something quite striking with the 57 % achieved over the standard Liraglutide.
Once-Weekly Dosing
It’s can also be easy to get one shot a week because semaglutide comes in a long-acting form. This is one of the major advantages that it has on a lot of patients over other injections that you have to give every day.
Cardiovascular Benefits
Like Liraglutide, Semaglutide has also been shown to reduce the risk of cardiovascular events such as heart attack and stroke in those who have type 2 diabetes.
Liraglutide Vs Semaglutide: How to Make a Choice
Both drugs come out as being very effective and the use of either could also be based on factors like:
- The preferences of the patients (injection daily or weekly)
- Insurance cover and charge
- Motives of weight loss intentions
- Tolerability and adverse events
- Healthy and risky in general
Safety consideration and hypothetical Side Effects
Companions consist of going through:
- Nausea
- Vomiting
- Diarrhea
- Appetite loss
- Constipation
Most of these side effects are mild and may get reduced over time as the body gets used to it. Both medicines are normally introduced in a low dosage and progressively raised to help in the reduction of pain.
FAQ’s
Will it be possible to move to another medication which is Semaglutide?
Yes, but these have to be done under the watch of your healthcare provider where appropriate medication adjustment and surveillance will be carried out.
Is there weight loss with both of the medications?
Yes, however Semaglutide has demonstrated more weight loss outcomes in the clinical trial than Liraglutide.
What are these drugs insulin?
No, Liraglutide, and Semaglutide are not insulin. They are agonists of GLP-1 receptors, which assist in dealing with blood sugar by the body.
Conclusion
Liraglutide and Semaglutide have changed the face of the management of diabetes type 2. Liraglutide has also enjoyed a long reputation as a safe drug promoting small weight loss and controlling blood sugar particularly among patients with a high risk of cardiovascular disease. Nevertheless, Semaglutide treatment extends these advantages with more stringent glycemic levels, more remarkable performance in weight reduction, and the ability to administer only once a week.
It is important that you ask your healthcare professional to help you know the best treatment suitable to your specific health objectives and health history. Most times it is quite possible to control your blood sugar and get better body conditions with the help of adequate therapy.
